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靶控输注瑞芬太尼与异丙酚在无痛肠镜中的应用 被引量:1

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摘要 目的探讨靶控输注瑞芬太尼复合异丙酚在无痛肠镜检查中的效果。方法选择200例ASAⅠ~Ⅱ级需行肠镜检查患者,随机分为P组,以40μg(/kg·min)的速率靶控输注异丙酚至患者睫毛反射和指令性反应消失,如检查中患者出现四肢活动则追加异丙酚30mg至活动消失;RF组以瑞芬太尼0.05μg(kg·min)加异丙酚40μg(kg·min)靶控输注至检查结束。术前、术中监测MAP、HR和SPO2。记录异丙酚总剂量、诱导时间、苏醒时间及患者体动率。结果与用药前比较,每组睫毛反射消失时MAP、HR均显著降低(P<0.05),肠镜检查时P组显著增高(P<0.05);RF组SPO2下降及苏醒时间缩短较P组显著(P<0.05),P组异丙酚用量、诱导时间、体动发生率比RF组非常显著增加(P<0.01)。术中无知晓、入睡快、苏醒快,术后恢复良好。结论靶控输注瑞芬太尼与异丙酚在无痛肠镜检查中是一种很好的麻醉方式。
作者 易洪章
出处 《中国现代医生》 2009年第12期113-114,共2页 China Modern Doctor
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