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幽门螺杆菌感染胃炎组织中IL-1β mRNA的表达 被引量:2

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摘要 以60例胃炎患者和60例健康者为研究对象,应用逆转录—聚合酶链式反应(RT-PCR)技术检测白细胞介素1(IL-1)mRNA表达,应用酶联免疫吸附试验(ELISA)检测幽门螺杆菌(Hp)抗体浓度。发现在胃体及胃窦部,Hp阳性组IL-1β mRNA表达阳性率均明显高于Hp阴性组,提示Hp可能通过影响胃窦部及胃黏膜IL-1β的产生量进而影响胃内酸分泌的途径,最终影响胃炎、胃癌的发展模式。
出处 《山东医药》 CAS 北大核心 2009年第16期47-48,共2页 Shandong Medical Journal
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