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术前血浆D-二聚体测定在大肠癌中的临床意义

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摘要 目的研究大肠癌患者血浆D-二聚体浓度的变化及意义。方法按随机原则设立大肠癌组34例,良性病对照组31例。分别于术前采血检测其血浆D-二聚体水平并对其进行统计分析。同时大肠癌组按照Dukes分期标准分为4个亚组,并对组间D-二聚体水平进行比较。结果大肠癌组的血浆D-二聚体水平显著高于对照组[(394.12±105.21)μg/L与(129.03±8.29)μg/L,P〈0.05。在大肠癌组的各亚组比较中,DukesD期患者的D-二聚体水平明显高于其他各期,分别为D期(800.00±287.94)μg/L、A期(180.00±58.31)μg/L、B期(170.00±33.50)μg/L、C期(250.00±86.60)μg/L,差异有统计学意义(P均〈0.05)。结论大肠癌患者血浆D-二聚体水平显著升高,并且对大肠癌的分期及预后可能有一定的指导意义。
出处 《中国综合临床》 2009年第5期538-539,共2页 Clinical Medicine of China
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