肝豆状核变性患者心理状况分析

The Analysis on the Mental Status of Patients with Hepatolenticular Degeneration

目的探讨肝豆状核变性(HLD)患者的心理状况。方法对58例住院HLD患者采用症状自评量表(Scl-90)进行测查,并与43名正常人进行对照。结果HLD患者的焦虑、敌对性、躯体化、抑郁、恐怖因子、阳性项目数与健康对照组比较差别有统计学意义(P<0.001,P<0.01);锥体外系症状为主的HLD患者(脑型)躯体化、焦虑、敌对性、恐怖因子均分高于肝损害为主的HLD患者(肝型,P<0.05)。结论HLD患者有许多心理症状,尤其是脑型HLD患者;在药物驱铜治疗的同时,应重视心理治疗,以提高临床疗效。

Objective To study the mental status of patients with hepatolenticular degeneration （HLD）. Method We used Symptom Check list 90 （Scl-90） to evaluate 58 patients with HLD, and compared with 43 normal people. Result The scores of the anxiety, hostility, somatization, depression, photie anxiety of the patient group are higher than those of the control group （P〈0.001 ,P〈0.01）. Positive items of the patient group are more than those of the control group（P〈0.01）. The scores of the somatization, anxiety, hostility, photic anxiety of the cerebral type HLD patients are higher than those of the liver type HLD patients （P〈0.05）. Conclusion Patients with HLD, especially cerebral type patients, have many mental symptoms. As soon as we treat patients with HLD by de-coppering, we ought to provide mental treatment as to promote the clinical effectiveness.