新生儿缺氧缺血性脑病194例临床分析

Clinical Analysis of Neonatal Hypoxic Ischemic Encephalopathy:a Report of 194 Cases

目的分析新生儿缺氧缺血性脑病的临床特点,提高对该病的认识。方法回顾性分析儿科194例新生儿缺氧缺血性脑病(HIE)患儿的临床资料。结果194例HIE患儿中痊愈136例(70.1%),好转38例(19.6%),放弃治疗及转外院17例,死亡3例,总有效率89.7%。结论足月儿有窒息、围产期高危因素、宫内窘迫者,需高度警惕缺氧缺血性脑病的可能,应结合临床及头颅CT综合考虑作出诊断,一经诊断应予以综合治疗及干预,使其避免发生严重的神经系统后遗症。

Objective To analyze the elinieal features of neonatal hypoxie isehemie eneephalopathy （HIE） and improve the cognition of the disease. Methods The clinical data of 194 neonate patients with HIE in our hospital were analyzed retrospectively. Results Among the 194 cases, 136 cases（70.1% ） reeovered,38 （ 19.6% ） improved, 17 gave up clinical treatment or transferred from hospital and 3 died, the total effective rate of 89.7%. Conclusion HIE was not unlikely in infants with anoxemia or high-risk faetors in perinatal stage. We should make a definite diagnosis based on head CT and elinieal features ,and perform timely intervention and treatment to prevent the serious sequela in nervous systems.