精神分裂症合并糖尿病患者临床特征的对照研究

Comparative study of clinical characteristic in patients with schizophrenia complicated by diabetes mellitus

目的探讨精神分裂症合并糖尿病患者的临床特征。方法使用自制调查表,收集30例精神分裂症合并糖尿病患者和30例单纯精神分裂症患者。结果精神分裂症合并糖尿病的患者,平均病程,复发次数和平均住院日显著高于单纯精神分裂症患者(P<0.05或<0.01)。精神分裂症合并糖尿病患者的临床症状显著重于单纯精神分裂症患者(P<0.05或<0.01)。精神分裂症合并糖尿病患者的疗效显著低于单纯精神分裂症患者(P<0.01)。结论精神分裂症合并糖尿病患者的临床症状重,治疗难度大。

Objective To investigate the clinical characteristics in patients with schizophrenia complicated by ＇diabetes mellitus. Methods Using self-made investigating table, the data of 30 patients with schizophrenia complicated by diabetes mellitus and 30 patients simple schizophrenia were collected and analyzed. Results The times of recurrence, average course of disease and mean in-hospital days in patients with schizophrenia complicated by diabetes mellitus were obviously higher than those of patients with simple schizophrenia （ P 〈 0.05 or 〈 0.01 ）. Their clinical symptoms were significantly more serious than those of patients with simple schizophrenia（ P 〈 0.05 or 〈 0.01 ）. The therapeutic effects in these patients were obviously worse than those of simple ones （ P 〈 0.01 ）. Conclusion The symptoms in patients with schizophrenia complicated by diabetes mellitus are much more severe than those of patients with simple schizophrenia, which are much more difficult to be treated.