C反应蛋白对支架内再狭窄严重程度的判定

Assessment of Restenosis with C-reactive Protein after Stenting Surgery

目的：探讨支架置入术后患者再狭窄发生时血清超敏C反应蛋白（hs-CRP）含量变化及其临床意义。方法：采用酶联免疫吸附法（ELSA）检测30例释放支架患者为对照组,不同时期hs-CRP含量和18例有再狭窄为治疗组hs-CRP含量变化。结果：治疗组（3-6）个月hs-CRS含量明显高于对照组,有统计学意义（P〈0.01）。结论：监测治疗组hs-CRP含量变化有助于判断狭窄的严重程度,评估预后,对预测和干预处理有一定的临床价值。

Objective：To assess the gravity of changes on serum level of hs- C-reactive protein （hs- CRP） during vascular restenosis period after stenting. Methods： All subjects were assigned in the control group in which the subjects had a restenosis after stenting and therapeutic group with no restenosis in block of 30 who were confirmed to meet the diagnostic criteria of ESC/NSTEMI in society of heart disease in Europe. Serum level of hs -CRP was measured by ELSA before and after 24hr, 72hr, 1 week, 3 months and 6 months stenting. Results： The hs - CRP content of therapeutic group is significantly higher than that of control group （P 〈 0.01 ） during 3 -6 months after stenting. Conclusions： Detection of serum level of hs - CRP is benefit for assessment of restenosis after stenting.