奥曲肽、清胰汤联合治疗重症急性胰腺炎24例疗效观察

Octreotide, Qingyi Tang Combined Treatment of Severe Acute Pancreatitis 24 Cases of Clinical Observation

目的:观察奥曲肽与清胰汤联合应用对重症急性胰腺炎(SAP)的治疗效果。方法:48例患者随机分为治疗组和对照组,对照组24例,给予禁食、胃肠减压、抑酸、奥曲肽及支持对症治疗:治疗组24例,加用清胰汤,余治疗同对照组。观察两组患者腹部症状及体征、排气、排便、血淀粉酶等恢复情况,以及住院日数和总有效率的比较。结果:治疗组在患者症状、体征的缓解,7d内血淀粉酶恢复及住院天数等方面均明显优于对照组。治疗组总有效率明显优于对照组(P<0.05)。结论:奥曲肽联合中药清胰汤治疗急性重症胰腺炎疗效明显,优于单纯奥曲肽等西医治疗。

Objective： To observe the effects ofoctreotide and Qingyi Tang Decoction joint application of severe acute pancreatitis （SAP） clinical treatment. Methods： 48 patients were randomly divided into treatment group and control group, 24 cases of the control group, given to fasting, gastrointestinal decompression, acid, octreotide and support symptomatic treatment; 24 cases of the treatmenl group, plus Qingyi Tang, more than treating the same the control group. The two groups were observed in patients with abdominal symptoms and signs, venting, defecation, blood enzymes of starch recovery, as well as the number of days of hospitalization and the total effective rate comparison. Results： In the treatment group in patients with symptoms and signs of remission, 7d the restoration of blood amylase and in-patient days and so much better than the control group. The total effective rate in treatment group was superior to control group （P 〈0.05）. Conclusions： Octreotide Qingyi Tang combined with traditional Chinese medicine treatment of severe acute panereatitis efficacy obviously, better than Western medicine, such as the treatment of oetreotide.