超声测量子宫内膜厚度在异位妊娠与自然流产鉴别诊断中的作用

Thickness in Differential Diagnosis of Ectopic Pregnancy and Spontaneous Abortion

目的:探讨子宫内膜厚度是否在异位妊娠与自然流产鉴别中有预测价值。方法:对96例疑似异位妊娠的患者采用阴道超声测量子宫内膜厚度及测定血清β-HCG值。结果:62例(64.6%)异位妊娠,34例(35.4%)自然流产,内膜厚分别为(5.41±0.24)mm、(8.57±1.26)mm,两组比较有显著性差异(P<0.05)。两组患者间孕龄和血β-HCG水平比较无显著性差异(P>0.05),93%的妊娠患者当内膜厚<7mm为异位妊娠,仅7%的妊娠患者当内膜厚≥7mm时为异位妊娠,二者相比有显著性差异(P<0.01)。结论:当血β-HCG较低时超声测定子宫内膜厚度对预测异位妊娠患者具有重要参考价值。

Objective： To determine whether endometrial stripe thickness is predictive of risk of ectopic pregnancy or spontaneous abortion, Methods： ninety-six women who suspected to have ectopic pregnancy were included in the study. The transvaginal ultrasonogram were performed on all patients to measure the endometrial stripe thickness and serum β-HCG measurement after the initial evaluation. All patients were followed until the definitive diagnosis was determined. Results： On follow-up examination 62（64. 6% ） were diagnosised as having ectopic pregnancy ,34 （35.4%） as having spontaneous abortion. In our study the mean endometrial stripe thickness of patients with ectopic pregnancies, spontaneous abortion was （5.41 ± 0. 24）mm, （8.57 ± 1.26 ）mm respectively. They had significant difference （P 〈 0. 05 ）. No correlation was found between gestational age or serum β-HCG in them（P 〉0.05 ）. 93% of the pregnancies with an endometrial stripe thickness 〈7mm were ectopic pregnancy. This was statistically significant when compare with 7% of pregnancies that were ectopic pregnancy when the endometrial stripe thickness was ≥ 7mm （P 〈 0. 01 ）. Conclusions： Transvaginal ultrasound examination of endometrial stripe thickness may be predictive of risk of ectopic pregnancy or spontaneous abortion when β-HCG below discriminatory zone.