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测定心肌型脂肪酸结合蛋白在早期诊断急性心肌梗死中的应用

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摘要 目的:探讨测定心肌型脂肪酸结合蛋白(HFABP)在临床诊断早期急性心肌梗死的应用效果。方法:选择65例胸痛患者采用快速检测患者发病0~3h,3~6h和6h后血清H—FABP,并与常规静脉血心肌肌钙蛋白cTnI肌酸激酶同工酶(CK—MB)结果比较,分析3种心肌标志物在诊断不同发病时段AMI的敏感性和特异性。结果:在0~3h和3~6h时段诊断AMI的敏感性H—FABP(66.7%、92.3%)明显高于cTnI(33.3%、6125%)CK—MB(0%、61.5%);特异性方面与CK—MB相当但明显优于cTnI。结论:H—FABP在AMI发生3h内较cTnI和cKMB更具有早期诊断实用价值。
出处 《中国误诊学杂志》 CAS 2009年第15期3575-3576,共2页 Chinese Journal of Misdiagnostics
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  • 1刘彩云,杨蔚,杜红,吴健,孙素莲,寿成超.人血清HER-2/neu胞外域蛋白检测方法的建立[J].中华检验医学杂志,2006,29(4):310-313. 被引量:6
  • 2Moss DW,Henderson AR.Clinical enzymology.In:Burtis CA,Ashwood ER.editors.Tietz Textbook of Clinical Chemistry.3rd ed[M]. Philadelphia:W.B.Saunders Company,1999.617-721.
  • 3Glatz JF,Van der Vusse GJ,Simoons ML,et al.Fatty acid-binding protein and the early detection of acute myocardial infarction[J].Clin Chim Acta,1998,272(1):87-92.
  • 4Seino Y,Tomita Y,Takano T,et al.Office Cardiologists cooperative study on whole blood rapid panel tests in patients with suspicious acute myocardial infarction:comparison between heart-type fatty acid-binding protein and troponin T tests[J].Circ J,2004,68(2):144-148.
  • 5Chan CP,Sanderson JE,Glatz JF,et al.A superior early myocardial infarction marker-human heart-type fatty acid-binding protein[J].Z Kardiol,2004,93(5):388-397.
  • 6Hayashida N,Chihara S,Akasu K,et al.Plasma and urinary levels of heart fatty acid-binding protein in patients undergoing cardiac surgery[J].Jpn Circ J,2000,64(1):18-22.
  • 7Nayashida N,Chihara S,Tayama E,et al.Influence of renal function on serum and urinary heart fatty acid-binding proteion levels[J].J Cardiovasc Surg(Torino),2001,42(6):736-740.
  • 8De Lemos JA,Antman EM,Morrow DA,et al.Heart-type fatty acid-binding protein as a marker of reperfusion after thrombolytic therapy[J].Clin Chim Acta,2000,298(1-2):85-97.
  • 9De Groot MJ,Muijtjens AM,Simoons ML,et al.Assessment of coronary reperfusion in patients with myocardial infarction fatty using acid-binding protein concentrations in plasma[J].Heart,2001,85(3):278-285.
  • 10Fransen EJ,Maessen JG,Hermens WT,et al.Peri-operative myocardial tissue injury and the release of inflammatory mediators in coronary artery bypass graft patiens[J].Cardiovasc Res,2000,45(4):853-859.

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