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HIV/HCV共同感染对HCV病毒清除及免疫功能的影响 被引量:2

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摘要 目的:研究HIV/HCV共感染患者血清中HCV病毒载量、CD4+T细胞计数及细胞因子等变化。方法:选取共感染者66例,HCV、HIV单独感染者38、34例和健康者33例。PCR检测HCV病毒载量;流式细胞仪检测CD4+T细胞计数;ELISA法检测IFN-γ和IL-10含量。结果:与HCV组相比,共感染组HCV病毒载量明显增高;CD4+T细胞计数明显降低;IFN-γ水平下降(P<0.01)。结论:共感染可加速HCV复制、降低IFN-γ水平;HCV病毒载量增高与CD4+T细胞数量无关。
出处 《中国误诊学杂志》 CAS 2009年第15期3594-3595,共2页 Chinese Journal of Misdiagnostics
基金 国家高新技术研究发展计划(863计划)项目(编号:2006AA02Z411) 北京市中医药管理局课题(编号:JJ-2006-24)
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参考文献4

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