高频超声对冠心病患者的颈动脉内-中膜厚度及斑块检测的临床研究

Clinical research of intima-media thickness and the spot piece detected by high frequency ultrasonic in patients with carotid disease

目的探讨颈动脉作为反映冠状动脉粥样硬化的体表窗口的可行性及在冠心病诊断中的临床意义。方法对48例有明确心绞痛症状但无心肌梗死病史患者、30例有心肌梗死病史的患者和45例正常人用高频超声分别测量颈动脉内-中膜厚度（IMT）及斑块发生率，并进行对照分析。结果心肌缺血组IMT平均为（0．88±0．24）mm，与心肌梗死组（1.08±0．19）mm差异无统计学意义，而较对照组（0．65±0．15）mm差异有统计学意义。心肌缺血组斑块发生率为58．3％（28／48），心肌梗死组为70．0％（21／30），对照组为13．3％（6／45）。结论本研究表明颈动脉的内-中膜厚度、斑块发生率与心肌缺血程度及病史长短有关联。高频超声检测颈动脉IMT及斑块发生率可作为监测冠心病患者的客观指标。

Objective To explore the intima-media thickness and the spot piece detected by high frequency ultrasonic in patients with carotid disease. Methods Forty eight symptomatic pectoris patients without myocardial infarction disease history, 30 patients with myocardial infarction disease history and 45 normal people were enrolled. The inside-middle membrane thickness （IMT） and manifestation of spot rate of carotid artery were detected by high frequency ultrasonic. Results The myocardial of IMT lacks the blood set （0.88 ± 0.24） mm and the myocardial infarction set（ 1.08 ± 0.19）mm, both have no obvious difference, but compare with normal set to have the obvious difference. A manifestation rate of spot： The myocardial lacks the blood set as 58.33% （28/48） ; the myocardial infarction set is 69.99% （21/30） ; the normal set is 13.33% （6/45）. Conclusion High frequency ultrasonic detecting carotid artery IMT and an occurrence of spot rates is valuable for patients with coronary artery disease.