摘要
目的:探讨口服避孕药的应用与宫颈上皮性鳞癌发病的关系。方法:采用Meta分析的方法,检索PubMed数据库,以及文献追溯等途径,对国外学者自1999年-2008年公开发表的有关口服避孕药的应用与宫颈上皮性鳞癌发病关系的研究文献应用RevMan4.2软件进行综合定量分析。结果:入选的8篇文献包括了3415个病例及4037个对照。以使用口服避孕药与否进行分组,计算使用OC组各研究结果合并的OR值为0.96,95%CI0.85-1.08。结论:使用口服避孕药尚不能认为增加宫颈癌的发病风险。
Objective：To explore the relationship between the use of oral contraceptives and the risk of cervical cancer. Methods：The references on the the relationship between the use of oral contraceptives and cervical cancer collected by database from 1999 to 2008 were adopted with research criteria and analyzed by means of meta - analysis. RevMan4.2 software was applied to process data. Results：Eight eligible studies were identified, including 3415 women with cervical cancer and 4037 controls. Compared with users of oral contraceptives,the relative risks of cervi- cal cancer increased with duration of never use were 0.96 （95% CI 0.85 - 1.08）. Concluslon：Using oral contr -aceptives would not increase the risk of cervical cancer.
出处
《现代肿瘤医学》
CAS
2009年第5期917-920,共4页
Journal of Modern Oncology
基金
国家自然科学基金资助(030107)
关键词
口服避孕药
宫颈癌
系统评价
META分析
oral contraceptive
cervical cancer
systematic review
Meta - analysis
