摘要
鞘氨醇单胞菌属的许多菌株能够合成结冷胶、沃仑胶、迪特胶等多种结构相似,物理性能多样的生物聚合物,统称为鞘氨醇胶。目前,结冷胶已经大规模的生产和应用,由于鞘氨醇单胞菌属的提出仅有十几年的历史,其他种类鞘氨醇胶的研究和开发才刚刚起步。本文综述了鞘氨醇单胞菌属分类研究的最新进展,以及鞘氨醇胶的结构、特性、生物合成途径、分子遗传学和基因工程的研究现状,并对今后的研究重点和方向进行了展望。
The genus Sphingomonas was established in 1990. Sphingomonas spp. synthesize sphingans, structurally related biopolymers such as gellan, welan and diutan. At present, only gellan is applied widely in foods and pharmaceuticals. The economic value of other sphingans has not been well explored, and related research of sphingans still remains limited. In the present review, we address the latest taxonomy developments of Sphingomonas, details about structure, characteristics and biosynthetic pathway of sphingans, current knowledge on the molecular genetics and genetic engineering of sphingans. In addition, we indicate future research needs.
出处
《微生物学报》
CAS
CSCD
北大核心
2009年第5期560-566,共7页
Acta Microbiologica Sinica
基金
国家自然科学基金(50674058)~~
关键词
鞘氨醇单胞菌
鞘氨醇胶
合成途径
基因工程
Sphingomonas sp.
sphingans
biosynthetic pathway
genetic engineering