多微孔胺基树脂的制备及其对胆红素的吸附性能

Preparation of aminated porous resin and for bilirubin adsorption

采用悬浮聚合法制备了一定尺寸的多微孔聚苯乙烯(PS)微球,然后通过Friedel-Crafts反应(用氯乙酰氯替代了有致癌性的氯甲醚)和胺化反应得到新型的胺基树脂,并对反应条件进行了优化。结果表明,利用最优化条件制备的胺基树脂,其离子交换容量为4.1587mmol/g。考察了新型树脂对胆红素的吸附性能,其吸附量最大可达30.85mg/g,吸附率可达80%。

Polystyrene microspheres （PS） were successfully prepared by suspension polymerization processes. Chloroacetylated polystyrene has been prepared by Friedel-Crafts acetylation of PS with chloroacetyl chloride. In this report, carcinogenic compound （chloromethylether etc.） was avoided. The effects of solvent, catalyst, acylating agent and reaction time were studied. Novel adsorption resins were obtained by synthesis of chloroacetylated polystyrene with amine. The influences of solvent, amine reagent and reaction time on ion exchange capacity were investigated. Under the optimized reaction condition, the ion exchange capacity of the prepared resins was 4.1587 mmol/g. The maximum amount of adsorbed bilirubin was 30.85 mg/g, the adsorption percentage was 80%.