New spindle morphogenesis model by Dynein, Nudel, and the spindle matrix
New spindle morphogenesis model by Dynein, Nudel, and the spindle matrix
摘要
It is well established that the mitotic spindle, the organelle responsible for chromosome segregation during mitosis, is built from microtubules, motor proteins, and associated structural and regulatory molecules. More controversial is the existence and identity of non-microtubule spindle components, collectively referred to as the matrix. What might be the role of a nonmicrotubule matrix？ A static matrix could bind motor proteins, and generate motion ofmicrotubules. This could be important for spindle assem- bly and function,
参考文献14
-
1Scholey, JM, Rogers GC, Sharp DJ. Mitosis, microtubules, and the matrix. J Cell Biol 2001; 154:261-266.
-
2Johansen KM, Johansen J. Cell and Molecular Biology of the Spindle Matrix. Int Rev Cytol 2007; 263:155-200.
-
3Leslie RJ, Hird RB, Wilson L, McIntosh JR, Scholey JM. Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles. Proc Natl Acad Sci USA 1987; 84:2771-2775.
-
4Hepler PK, Wolniak SM. Membranes in the mitotic apparatus: their structure and function. Int Rev Cytol 1984; 90:169- 238.
-
5Lince-Faria M, Maffini S, Orr B, et al.Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator. J Cell Biol 2009; 184:647-657,
-
6Tsai MY, Wang S, Heidinger JM, et al. A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science 2006; 311:1887-1893.
-
7Ma L, Tsai MY, Wang S, et al. Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. Nat Cell Biol 2009; 11:247-256.
-
8Efimov VP, Morris NR. The LIS1- related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO 11 protein. J Cell Biol 2000; 150:681-688.
-
9Li J, Lee WL, Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat Cell Biol 2005; 7.686-690.
-
10Feng Y, Olson EC, Stukenberg PT, Flanagan LA, Kirschner MW, Walsh CA. LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron 2000; 28:665-679.
-
1New Progress in Cell Biology Research[J].Science Foundation in China,2009,17(1):5-5.
-
2陆德.规章[J].意林（少年版）,2012(17):23-23.
-
3朱行.欧盟与美国规范转基因作物的比较和区别[J].饲料世界,2000(9):32-33.
-
4星河.从属于别人的生命[J].知识就是力量,2013(4):30-31.
-
5Jing Li,Xiaoqian Liu,Ji Liao,Jie Tian,Jue Wang,Xin Wang,Jiezhong Zhang,Xingzhi Xu.MYPT1 Sustains Centromeric Cohesion and the Spindle-Assembly Checkpoint[J].Journal of Genetics and Genomics,2013,40(11):575-578.
-
6Yi Huang,Xiao-Xia Wang,Dong-Dong Sun,Ze-Xin Zhang,Wan-Wan Yang,Tian Shao,Han Han,Er-Fei Zhang,Zhong-Shu Pu,Zuo-Xu Hou,Hai-Long Dang,Li-Ze Xiong,Li-Chao Hou.Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models[J].Chinese Medical Journal,2017(7):840-853. 被引量：2
-
7赵宝华,许崇波,段相林,朱平.抗α毒素单链抗体基因表达及生物学特性研究[J].中国预防兽医学报,2002,24(2):116-119.
-
8马永平.责任重于泰山[J].现代焊接,2005(4):3-3.
-
9Wei-chang SHEN Xu WANG Wei-ting QIN Xue-feng QIU Bing-wei SUN.Exogenous carbon monoxide suppresses Escherichia coli vitality and improves survival in an Escherichia coli-induced murine sepsis model[J].Acta Pharmacologica Sinica,2014,35(12):1566-1576. 被引量：9
-
10周济谱.近亲应远离你的团队[J].企业文化,2009(5):71-72.
