山冈橐吾碱clivorine致DNA损伤的研究
出处
《毒理学杂志》
CAS
CSCD
北大核心
2009年第2期121-123,共3页
Journal of Toxicology
基金
国家自然科学基金重点项目(30530840)
上海市科技启明星计划(山冈橐吾碱诱导肝细胞凋亡的分子机制07QA14049)
参考文献15
-
1Roeder E. Medicinal plants in China containing pyrrolizidlne alkaloids. Pharmazie, 2000,55 : 711-726.
-
2Stegelmeier BE, Edgar JA, Colegate SM, et al. Pyrrolizidine alkaloid plants, metabolism and toxicity. J Nat Toxins, 1999, 8:95-116.
-
3Zuckerman M, Steenkamp V, Stewart MJ. Hepatic venoocclusive disease as a result of a traditional remedy: confirmation of toxic pyrrolizidine alkaloids as the cause, using an in vitro technique. J Clin Pathol,2002,55:676-679.
-
4Gordon GJ, Coleman WB, Grisham JW. Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine. Exp Mol Pathol, 2000,69 : 17- 26.
-
5Xia Q, Chou MW, Lin G, et al. Metabolic formation of DHPderived DNA adducts from a representative otonecine type pyrrolizidine alkatoid clivorine and the extract of Ligularia hodgsonnii hook. Chem Res Toxicol.2004.17 :702-708.
-
6Laine MW, Jones AD, Wilson DW, et al. Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells. J Biol Chem ,2000,275:29091-29099.
-
7Wagner JG, Petty TW, Roth RA. Characterization of monocrotaline pyrrole-induced DNA cross-linking in pulmonary artery endothelium. Am J Physiol, 1993,264 : 517-522.
-
8Ji LL, Zhang M, Sheng YC, et al. Pyrrolizidine alkaloid clivorine induces apoptosis in human normal liver L-02 cells and reduces the expression of p53 protein. Toxicol In Vitro, 2005,19:41-46.
-
9Ji LL, Zhao XG, Chen L, et al. Pyrrolizidine alkaloid clivorine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein kinase in L-02 cells. Toxicon, 2002,40 : 1685-1690.
-
10Scott V, Clark AR, Docherty K. The gel retardation assay.Methods Mol Biol,1994,31:339-347.
-
1柳晓泉,林鸽,王广基,钱之玉.山冈橐吾碱在雌性大鼠肝微粒体内的代谢(英文)[J].中国药理学与毒理学杂志,2001,15(6):413-417. 被引量：4
-
2季莉莉,陈莹,王峥涛.山冈橐吾碱对HEK293细胞谷胱甘肽含量及相关酶活力的影响[J].毒理学杂志,2007,21(3):205-207. 被引量：1
-
3翁福海,王佩君.花生四烯酸与细胞色素P—450酶系研究进展[J].天津医学院学报,1994,18(1):106-109.
-
4柳晓泉,林鸽,王广基,钱之玉.人肝CYP3A参与了山冈橐吾碱的代谢及其肝毒性代谢物的形成(英文)[J].中国药理学与毒理学杂志,2002,16(1):15-20. 被引量：5
-
5王军,王长虹,王峥涛.吡咯里西啶生物碱的细胞毒性及致毒机制研究进展[J].国际药学研究杂志,2007,34(4):246-249. 被引量：24
-
6吴继平,郭怀芳.三唑类抗真菌药——D-0870[J].药学进展,2001,25(1):58-59. 被引量：1
-
7韩佳寅,梁爱华,高双荣.含吡咯里西啶生物碱植物的特殊毒性及致毒机制研究进展[J].中国中药杂志,2011,36(10):1397-1401. 被引量：19
-
8姚军,戚新明,任进.野百合碱毒性机制研究进展[J].毒理学杂志,2014,28(3):237-241. 被引量：3
-
9季莉莉,檀爱民,汤俊,张勉,王峥涛.几种吡咯里西啶类生物碱对肝细胞毒性的探讨[J].中国天然药物,2004,2(4):239-241. 被引量：11
-
10季莉莉,王峥涛.p38 MAP激酶在山冈橐吾碱肝细胞毒性中的作用[J].中国药理学与毒理学杂志,2007,21(4):278-282. 被引量：2
