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PCNA在L-02肝细胞用氢醌处理后的表达

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作者 胡恭华 庄志雄 庾蕾 黄海燕 袁建辉
机构地区 赣南医学院预防医学系 深圳市疾病预防控制中心
出处 《毒理学杂志》 CAS CSCD 北大核心 2009年第2期124-126,共3页 Journal of Toxicology
基金 国家重点基础研究发展计划(973)项目(2002CB5129032002CB512904)
关键词 氢醌 L-02肝细胞 增殖细胞核抗原
分类号 R994.6 [医药卫生—毒理学]
  • 相关文献

参考文献9

  • 1Cen SM, Gaspar J, Silva ID, et al. Mechanisms of induction of chromosomal aberrations by hydroquinone in V79 cells. Mutagenesis, 2003,18:491-496.
  • 2Lindsey RH, Bender RP, Oshemff N. Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase Ⅱ alpha: 1, 4-hydmquinone is a topoisomerase Ⅱ poison. Chem Res Toxicol, 2005,18 : 761-770.
  • 3Gaskell M, McLuckie KI, Farmer PB. Comparison of the mutagenic activity of the benzene metabolites, hydroquinone and parabenzoquinone in the supF forward mutation assay: a role for minor DNA adducts formed from hydroquinone in benzene mutagenicity. Mutat Res, 2004, 554 : 387-398.
  • 4McCue JM,Lazis S, John C J, et al. Hydroquinone and catechol interfere with T cell cycle entry and progression through the Gi phase. Mol Immunol, 2003,39 : 995-1001.
  • 5Terasaka H, Morshed SR, Hashimoto K, et al. Hydroquinoneinduced apoptosis in HL-60 cells. Anticancer Res, 2005,25: 161-170.
  • 6Li L,Peterson CA, Zhang X, et al. Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesis. Nucleic Acids Res,2000,28 : 1424-1427.
  • 7Sourisseau T, Georgiadis A, Tsapara A, et al. Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONABP/DbpA. Mol Cell Biol, 2006,26 : 2387-2398.
  • 8Kannouche PL Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA:A possible mechanism for the polymerase switch in response to DNA damage. Mol Cell,2004, 14:491-500.
  • 9胡恭华,庄志雄,夏芳莲,涂晓志,纪卫东,杨建平,沙焱.氢醌对L-02肝细胞DNA损伤及细胞周期的影响[J].环境与健康杂志,2007,24(4):201-203. 被引量：6

二级参考文献11

  • 1[1]Decaprio AP.The toxicology of hydroquinone relevance to occupational and environmental exposure[J].Crit Rev Toxicol,1999,29:283-330.
  • 2[3]Lindsey RH Jr,Bender RP,Osheroff N.Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase Ⅱ alpha:1,4-hydroquinone is a topoisomerase Ⅱ poison[J].Chem Res Toxicol,2005,18:761-770.
  • 3[4]Bironaite D,Siegel D,Moran JL,et al.Stimulation of endothelial IL-8 (Eil-8) prodction and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells[J].Chem Biol Interact,2004,149:177-188.
  • 4[7]Gaskell M,McLuckie KI,Farmer PB.Comparison of the mutagenic activity of the benzene metabolites,hydroquinone and parabenzoquinone in the supF forward mutation assay:a role for minor DNA adducts formed from hydroquinone in benzene mutagenicity[J].Mutat Res,2004,554:387-398.
  • 5[8]Gaskell M,McLuckie KI,Farmer PB.Comparison of the repair of DNA damage induced by the benzene metabolites hydroquinone and p-benzoquinone:a role for hydroquinone in benzene genotoxicity[J].Carcinogenesis,2005,26:673-680.
  • 6[9]McCue JM,Lazis S,John Cohen J,et al.Hydroquinone and catechol interfere with T cell cycle entry and progression through the G1 phase.[J].Mol Immunol,2003,39:995-1001.
  • 7[10]Singh NP,McCoy MT,Tice RR,et al.A simple technique for quantitation of low levels of DNA damage in individual cells[J].Exp Cell Res,1988,175:184-191.
  • 8孟紫强.应用^(32)P-后标记技术对苯醌和氢醌处理人血淋巴细胞形成DNA加合物的研究[J].中国环境科学,1997,17(3):272-275. 被引量：13
  • 9常平,戴宇飞,李桂兰.苯及其代谢产物在小鼠骨髓中形成DNA加合物的实验研究[J].中华劳动卫生职业病杂志,1999,17(4):196-199. 被引量：6
  • 10朱志良,庄志雄,黄钰,籍涛.单细胞凝胶电泳图像分析系统的研制及应用[J].中华劳动卫生职业病杂志,2001,19(4):298-300. 被引量：89

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毒理学杂志
2009年 第2期

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