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卵巢内膜异位囊肿相关性不育IVF疗效观察 被引量：1

Outcome of IVF in Patients with Endometriosis Associated Infertility
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摘要 目的:为了探讨卵巢囊肿对IVF各个环节的影响。方法:回顾性分析卵巢内膜异位囊肿(≥3cm)患者行IVF治疗时的反应及妊娠结局,并以输卵管相关性不孕患者为对照组进行比较。结果:卵巢囊肿组周期取消率高于对照组(P<0.01),注射hCG日E2浓度、每周期回收胚胎数均低于对照组(P<0.05);组间胚胎种植率、分娩率均无差异(P>0.05)。结论:卵巢囊肿患者卵巢反应差,而子宫内膜容受性可能无改变,分娩率无差异;但卵巢囊肿组周期取消率高,IVF治疗预后不如输卵管因素不育患者。 Objective： To research the influence of the endometrioma to all the process of IVF. Methods： The ovarian response and the outcome of IVF were retrospectively analyzed for patients with endometriomas （≥ 3 cm） undergoing IVF-ET （EMS group）.The patients with tubal factor associated infertility acted as the control. Results： There were statistically significant differences between the two groups in the cancelling rate （P〈0.01）, the E2 concentration in the day of hCG injection （P〈0.05）, and obtained embryos （P〈0.05）.There were no statistically significant differences in the implantation rate and delivery rate （P〉0.05）. Conclusion： The patients with endometriomas had a poor response to the Gn. The endometrial accessibility in patients with endometriomas seemed not to be affected by the presence of endometriomas. But considering the higher cancelling rate, the prognostic for the patients with endometriomas was worse than the patients with tubal factor associated infertility.
作者 毛艳红 周春 Annie Zaccabri
机构地区 武汉大学医学部第二临床学院 武汉大学中南医院妇产科 PMA
出处 《生殖与避孕》 CAS CSCD 北大核心 2009年第4期221-225,共5页 Reproduction and Contraception
关键词 子宫内膜异位症 卵巢囊肿 不孕 体外受精 severe endometriosis endometrioma infertility in vitro fertilization （IVF）
分类号 R711.75 [医药卫生—妇产科学] R711.6 [医药卫生—妇产科学]
  • 相关文献

参考文献12

  • 1庞厚清,李尚为,李蕾.子宫内膜异位症伴不育治疗进展[J].生殖医学杂志,2005,14(3):185-188. 被引量：3
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  • 6Suganuma N, Wakahara Y, Ishida D, et al. Pretreatment for ovarian endometrial cyst before in vitro fertilization. Gynecol Obstet Invest, 2002, 54(Suppl.1):36-42.
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二级参考文献38

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共引文献4

同被引文献7

  • 1Pabuccu R, Onalan G, Goktolga U, et al. Asipiration of ovarian endometriomas before intracytoplasmic sperm injection. Fertil Steril, 2004, 82(3):705-11.
  • 2Dmowski WP, Pry M, Ding J, et al. Cycle-specific and cumulative fecundity in patients with endometriosis who are undergoing controlled ovarian hyperstimulation intrauterine inselnination or in vitro fertilization-embryo transfer. Fertil Steril, 2002, 78(4):750-6.
  • 3Makrydimas G, Sotiriadis A, Paraskevaidis E. Results of IVF in women with endometriosis. J Gynecol Obstct Biol Reprod (Paris), 2003, 32(8 Pt 2):S45-7.
  • 4Zikopoulos K, Kolibianakis EM, Devroey P. Ovarian stimulation for in vitro fertilization (IVF) for women with endometriosis. Acta Obstet Gynecol Stand, 2004, 83(7): 651-5.
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  • 6Surrey ES, Silverberg KM, Surey MW, et al. Efect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis. Fertil Steril, 2002, 78(4):699-704.
  • 7王丽,黄萍,刘伟信,赵成元,严风英.不同降调节方案对子宫内膜异位症患者IVF-ET妊娠结局的影响[J].生殖与避孕,2009,29(9):613-616. 被引量：11

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生殖与避孕
2009年 第4期

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