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受精后精子线粒体的命运 被引量:4

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摘要 人们普遍认为线粒体基因的遗传方式为母系遗传,精子线粒体在各种动物胚胎中的命运在很大程度上取决于核基因组与线粒体基因组间的相容性,而与精子线粒体相关的有些细胞组分被观察到能够在受精过程中得到传递,并且父系线粒体的遗传也在患者和种间杂交中被发现。然而用ICSI与IVF产生的正常后代中并没有发现父系mtDNA,反而在异常胚胎中检测到父系mtDNA.。本文通过对多种动物(如人、牛、小鼠和大鼠)精子线粒体在受精后的生物学特征进行总结,分析了其消失的可能机制及产生这种结果的原因。
出处 《生殖与避孕》 CAS CSCD 北大核心 2009年第4期244-248,共5页 Reproduction and Contraception
基金 国家“973”项目(编号:2004CB518806) 国家自然科学基金项目(编号:30770242)
关键词 精子 线粒体 命运
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同被引文献77

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  • 2陈晖,陈松,费江枫,赵跃华,金伟,曹坚,费仁仁.1050例不育男性精子碱性核蛋白的分析[J].生殖医学杂志,2005,14(3):135-138. 被引量:15
  • 3刘德一,H.W.Gordon Baker.精子功能检测与男性不育诊治的新进展[J].中华男科学杂志,2007,13(2):99-109. 被引量:66
  • 4陈慧,苏迎春,孙莹璞.线粒体在卵子和早期胚胎发育中的研究[J].国外医学(计划生育.生殖健康分册),2007,26(2):60-63. 被引量:5
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