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热休克蛋白70在赛来昔布联合热疗治疗胰腺癌中的作用

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摘要 热休克蛋白（HSP）又被称为是“伴侣蛋白”，它在细胞生长、发育、分化、基因转录等功能方面发挥重要作用，在多种肿瘤细胞表面都有它过度表达的现象。近年来的研究发现，HSP参与机体特异的抗肿瘤免疫反应，且HSP表达量与肿瘤免疫原性强弱密切相关，与肿瘤的恶性程度及患者的预后密切相关。
作者 刘丽燕 王兴鹏 姜立新 吴恺 杨佳芳
机构地区 上海交通大学附属第一人民医院消化科 同济大学医学院附属第十人民医院消化科 上海交通大学附属第六人民医院B超室
出处 《中华胰腺病杂志》 CAS 2009年第2期126-127,共2页 Chinese Journal of Pancreatology
关键词 热休克蛋白70 赛来昔布 胰腺癌 肿瘤细胞表面 抗肿瘤免疫反应 治疗 热疗 肿瘤免疫原性
分类号 R735.9 [医药卫生—肿瘤]
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参考文献7

  • 1Kramer G,Steiner GE,Grobl M,et al.Response to sublethal heat treatment of prostatic tumor cells and of prostatic tumor infiltrating T-cells.Prostate.2004,58:109-120.
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  • 4刘丽燕,王兴鹏,姜立新,吴恺,杨佳芳,臧丽娟.赛来昔布联合热疗治疗胰腺癌的研究[J].中华胰腺病杂志,2008,8(1):31-34. 被引量：1
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二级参考文献20

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中华胰腺病杂志
2009年 第2期

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