糖尿病防治的策略转变——从关注糖化血红蛋白到着眼心血管事件

The Changes of Strategy in Diabetes——from Focus on Glycosylated Hemoglobin to Avoiding Cardiovascular Events

通过对2型糖尿病心血管终点事件的观察,更多的临床证据提示,糖尿病的治疗目标应该以减少心血管事件为主。糖尿病防治从策略上发生了两个转变,即以血糖为中心转向以防治心血管事件为中心的多危险因素综合防治策略;以糖化血红蛋白检测作为血糖评价的金标准转向以血糖量、质、时程控制的全面评价策略。

Several recent trials have led to contradictory outcomes in relation to the issue of glycemic control and cardiovascular complications in patients with Type Ⅱ diabetes. The major target of diabetes treatment is to reduce cardiovascular events. Only relying on the glycosylated hemoglobin as the ＂gold standard＂ of the maintenance of tight glycemic control should be changed. A multi-- pronged approach to address the total cardiovascular risk factors is imperative. The best practice model for glycemic goals should include the quantity, quality and time course of glycemic exposure.