分子基逻辑材料

Molecular Logic Function Materials

在适当的条件下分子开关将输入的信息转换为输出信号,利用这一特点,可在分子体系根据二进位布尔逻辑规则实现信号转换。目前,用化学体系进行基本的布尔逻辑功能执行(PASS、YES、NOT、AND、NAND、OR、NOR、XNOR和INH)都已成为可能。在此基础上,逻辑门的整合与编程,以及更进一步的复杂分子运算开始受到人们的关注。迄今为止,以高灵敏性的荧光输出信号为主,人们在分子水平上设计实现了多种复杂的逻辑电路,包括组合逻辑电路和时序逻辑电路等,并开始涉及信息处理的安全平台设计。本文主要介绍了近年来用分子荧光开关体系模拟数字逻辑电路过程中所取得的最新进展,对分子逻辑电路研究的热点和问题进行了展望。

The mimicry of some elementary functions of neurons and electronic computers at the molecular scale has been attracting more and more interest, which has strongly pushed chemists to explore digital logic function and circuits at the molecular level for the purpose of molecular computing and biocomputer. As molecular switches convert input stimulations into output signals, the principles of binary Boolean logic can be applied to the signal transduction operated by molecules under appropriate conditions. Implementation of the most common Boolean functions （ PASS, YES, NOT, AND, NAND, OR, NOR, XOR, XNOR, and INH） with chemical systems is possible now. Holding these basic logic functions in hands, the chemists are devoting to novel computational architectures of complicated functions, as well information security in the molecular platform, to create a molecular analogue for every electronic product. A molecular 2：1 multiplexer comprises two photochromic moieties, dihydropyrene and dihydroindolizine units, linked to a central porphyrin to perform as a combinational circuit to connect any one of several possible inputs to an output. Molecular sequential logic requires the control of the kinetic behavior of the chemical system. A molecular keypad lock and crossword puzzles and logic memory are capable based on a molecular species in solution whose fluorescence is switched on only in response to a correct sequence of input signals, which are reminiscent of electronic keypad locks, a commonsecurity device that can control the opening of a door or a safe. An approach to the assembly of the biomolecular keypad lock using the enzyme-based networking system is also realized. Further, a molecular computing platform in defending against information risk is constructed, where chemical-encoded user identity information can be transmitted from sequential logic unit to combinational logic circuit, and hence resulting in the user-specific digital functionalities.