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女性泌尿道医院感染与社区获得性感染大肠埃希菌β-内酰胺酶检测及耐药性比较

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摘要 目的了解引起女性泌尿道医院感染(HI)和社区获得性感染(CAl)的大肠埃希菌耐药性及β-内酰胺酶检出率的差异性,以指导抗菌药物的合理使用。方法收集住院、社区女性泌尿道感染分离的大肠埃希菌作为受试菌,采用Kirby-Bauer法进行药敏试验,采用三维试验检测大肠埃希菌产ESBLs和AmpC酶。结果386株大肠埃希菌分离株中HI 245株,CAI 141株:ESBLs和AmpC酶总检出率为34.7%(134/386),HI和CAI的检出率分别为46.5%(114/245)和14.2%(20/141),CAI株对选用抗生素的总耐药率低于HI株。结论大肠埃希菌耐药性严重,HI组耐药率明显高于CAI组,且产生超广谱β-内酰胺酶和AmpC酶。
机构地区 青田县人民医院
出处 《浙江实用医学》 2009年第2期159-160,共2页 Zhejiang Practical Medicine
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