正交法研究α-氯环己烷羧酸的合成

RESEARCH ON SYNTHESIZING α-CHLORINE CYCLOHEXANECARBOXYLIC ACID BY KROENECKER METHOD

利用正交法研究环己酮在相转移催化剂溴化十六烷基三甲铵存在下与氯仿和水作用，一步合成α－氯环己烷羧酸，找到了最佳的合成条件，产率可达５４％．

This research used kroenecker method for cylohexanone reacting with chloroform and water under the existence of phase-transfer catalyst CTMAB, synthesizing αchlorine syclohexane carboxylic acid in one step. Best synthesizing conditions are found, The production rate can be up to 54%.