纤维蛋白与多发性硬化
摘要
纤维蛋白结构复杂,功能多样,不仅在凝血-纤溶过程中,而且在神经炎性疾病及变性病中发挥重要作用。在多发性硬化中纤维蛋白具有多方面作用,不仅参与血-脑脊液屏障通透性增加及炎性细胞浸润引起轴索损害的过程,而且通过细胞因子的调控等发挥多种生物学功能。
出处
《中国神经免疫学和神经病学杂志》
CAS
2009年第3期221-224,共4页
Chinese Journal of Neuroimmunology and Neurology
参考文献17
-
1Adams RA, Passino M, Sachs BD, et al. Fibrin mechanisms and functions in nervous system pathology[J]. Mol Interv, 2004,4(3) :163-176.
-
2Gveric D, Herrera B, Petzold A, et al. Impaired Iibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors [J]. Brain, 2003, 126 (Pt7) :1590-1598.
-
3Rubel C, Fernandez GC, Dran G, et al. Fibrinogen promotes neutrophil activation and delays apoptosis [J]. J Immunol(Baltimore, Md :1950), 2001,166 (3):2002-2010.
-
4Fuller GM, Zhang Z. Transcriptional control mechanism of fibrinogen gene expression[J]. Ann NY Acad Sci, 2001,936:469-479.
-
5Esmon CT. Does inflammation contribute to thrombotie events? [J].Haemostasis, 2000,30(Suppl 2) : 34-40.
-
6Akassoglou K, Yu WM, Akpinar P, etal. Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation [J].Neuron, 2002, 33 (6):861-875.
-
7Sahni A, Odrljin T, Francis CW. Binding of basic fibroblast growth factor to fibrinogen and fibrin[J]. J Biol Chem, 1998,273(13) :7554-7559.
-
8Sahni A, Sporn LA, Francis CW. Potentiation of endothelial cell proliferation by fibrin(ogen)-bound fibroblast growth factor-2[J]. J Biol Chem, 1999,274 (21):14936-14941.
-
9Sahni A, Francis CW. Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation[J]. Blood, 2000,96 (12) : 3772-3778.
-
10Akassoglou K, Kombrinck KW, Degen JL, et al. Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury[J]. J Cell Biol, 2000, 149(5) : 1157-1166.
-
1刘欣,孟宏音,刘廷磊.脑干出血预后分析[J].河南实用神经疾病杂志,2004,7(2):56-56. 被引量:3
-
2王文忠.丘脑出血38例临床分析[J].健康大视野(医学版),2006,14(1):62-62.
-
3唐庆希,陆曦,江红玲.丘脑出血的临床特点(附85例报告)[J].中国综合临床,2003,19(12):1086-1087. 被引量:12
-
4李春明.原发性脑干出血的预后因素分析(附78例报告)[J].广西医学,2008,30(1):106-107.
-
5侯艳秋,周荣富,高俊凤,沈群,汤秀兰,夏雯.脑血栓患者血浆t-PA、PAI及D-二聚体检测的意义(附19例报告)[J].南京医科大学学报(自然科学版),1999,19(3):195-195. 被引量:1
-
6毛旭强,王晓明.ABCD2评分联合D-二聚体评估老年性短暂性脑缺血进展为脑梗死的概率[J].中国老年学杂志,2015,35(21):6255-6256. 被引量:1
-
7刘春红,李静.血浆D-二聚体在肿瘤中的应用[J].国际肿瘤学杂志,2016,43(3):198-200. 被引量:1
-
8谢卫民.血塞通注射液治疗脑梗死30例疗效观察[J].赣南医学院学报,2010,30(6):943-943. 被引量:1
-
9王广民,高宝娟.原发性脑干出血6例临床分析[J].临床医药实践,2005,14(7):524-524. 被引量:1
-
10邵延坤,饶明俐.组织型纤溶酶原激活物及其抑制物与缺血性脑血管病[J].中风与神经疾病杂志,2002,19(3):188-190. 被引量:2