摘要
目的:研究E-cadherein、CD44v3、CD44v6在涎腺多形性腺瘤中的表达,旨在探讨细胞表面糖蛋白在涎腺多形性腺瘤中表达及意义。方法:应用免疫组化方法检测30例涎腺多形性腺瘤E-cadherein、CD44v3、CD44v6的表达。结果:E-cadherein在涎腺多形性腺瘤阳性(63.3%)表达,CD44v3在涎腺多形性腺瘤阳性(73.3%)表达,CD44v6在涎腺多形性腺瘤中呈强阳性表达(86.7%)。结论:细胞表面糖蛋白表达在涎腺多形性腺瘤呈阳性表达,提示瘤细胞同质粘附力较强,可能是涎腺多形性腺瘤不易发生浸润、转移的原因。
Objective ：To investigate the expression of E -cadherein , CD44v3 and CD44v6 in the polymorphic adenoma of salivary glands. Method： Using immunohistochemistry technology to detect the expression of E - cadherein, CD44v3 and CD44v6 in 30 cases of polymorphic adenoma of salivary glands. Result： The expression of CD44v3 was positive in 73.3% cases within 30 paraffin - embedded sections, compared with E -cadherein （63.3%）, while CD44v6, 86.7% were positive. Conclusion： The high expression of E - cadherein , CD44v3 and CD44v6 maybe the reason of the low invasive ability and migration of polymorphic adenoma of salivary glands.
出处
《河北医学》
CAS
2009年第5期505-508,共4页
Hebei Medicine
基金
佛山科学技术学院校级重点课题基金资助
