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糖皮质激素在炎症调节中的作用 被引量:8

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摘要 糖皮质激素作为一种重要的肾上腺皮质激素,是临床常用的抗炎药物。对其抗炎机制的探讨已经深入到分子水平。该药主要从基因水平发挥作用,经直接和间接途径抑制炎性因子的合成、转录。近年来的许多报道证明,糖皮质激素还具有促炎作用,在外循环中,其作用方式与浓度、给药时间和机体免疫系统状态密切相关,呈现低浓度促炎、高浓度抗炎的复杂模式,对糖皮质激素在炎症调节中的具体作用和机制有待进一步研究。
作者 王明玮
出处 《医药导报》 CAS 2009年第5期626-628,共3页 Herald of Medicine
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