CT引导经导管动脉化疗栓塞治疗肝细胞癌

CT-guided transcatheter arterial chemoembolization for hepatocellular carcinoma

目的探讨CT引导经导管动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)治疗肝细胞癌(hepatocellular carcinoma,HCC)的初步疗效,分析局部复发的危险因素。方法对32例患者的34个HCC病灶进行了CT引导TACE治疗。结果32例中26例实现局部控制,6例出现局部复发。采用Logistic回归分析发现,TACE治疗后中央型HCC病灶是局部复发的危险因素(P=0.0408)。结论CT引导TACE是治疗小HCC的好方法,其局部控制率高、复发率低。中央型HCC是TACE术后局部复发的危险因素。

Objective To evaluate initial therapeutic effects of CT-guided transcatheter arterial chemoembolization （TACE） on hepatocellular carcinoma （HCC） and analyze risk factors for local recurrence following TACE. Method CT-guided TACE was performed on 34 small HCC lesions in 32 patients with HCC. Results Local control was achieved in 26 cases and local recurrence developed in 6 cases. Logistic analysis showed that centrally located HCC lesions were likely to develop local recurrence（P=-0.040 8）. Conclusions CT-guided TACE is effective to treat small HCC lesions, with a higher local control rate and a lower recurrence rate. Centrally located HCC lesion is a risk factor for developing local recurrence after TACE.