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瘦素对HSC—T6细胞基质金属蛋白酶-2基因表达、蛋白分泌及酶活性的影响 被引量:2

Effects of rat recombinant leptin on matrix metalloproteinase- 2 gene expression, protein level and enzymatic activity in HSC- T6 cells
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摘要 本实验采用逆转录聚合酶链反应(RT-PCR)、酶联免疫吸附试验(ELISA)及酶谱法分别测定瘦素对肝星状细胞(HSC)基质金属蛋白酶2(MMP-2)mRNA表达、蛋白分泌及酶活性的影响,以进一步了解瘦素致纤维化的机制。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2009年第5期383-384,共2页 Chinese Journal of Hepatology
关键词 肝纤维化 肝星状细胞 基质金属蛋白酶-2 瘦素 Liver fibrosis Hepatic stellate cells Matrixmetalloprotenase-2 Leptin
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