芬太尼弹性输液泵静脉持续注射治疗重度癌痛的疗效观察

Effects of fentanyl intravenous continuous infusion with blastomory system on cancer pain

目的研究芬太尼弹性输液泵静脉持续注射治疗重度癌痛的疗效以及副作用。方法本组患者60例，均为重度癌痛，不适应放疗以及化疗者。经锁骨下静脉或肘静脉置管后连接弹性输液泵，内含药物为芬太尼1-5～2mg／m^2（体表面积），氟哌利多10mg以0．9％生理盐水稀释到250ml，持续输注速度2ml／h。观察镇痛疗效与用药后相关副作用：恶心、呕吐、便秘、尿潴留、呼吸状态、镇静程度等。结果疼痛完全缓解15例（25％）；部分缓解33例（55％）；轻度缓解12例（20％）；无效0例。结论对于重度癌痛患者，使用芬太尼弹性输液泵静脉持续注射是一种安全、有效、方便、经济的镇痛方法。

Objective To observe the effects and side-effects of fentanyl intravenous continuous infusion with blastomory system on cancer pain. Methods Sixty patients with severe cancer pain, not suitable for radiotherapy or chemotherapy, were enrolled in this study. The catheters via sub -clavicle or elbow vein were connected to the infusion pump. Fentanyl 1.5-2 mg/m^2 and droperidol 10mg were dissolved in 0.9% sodium chloride 250 ml in the pump. The infusion speed was 2 ml/h. Then the analgesic effect and side-effects were observed and recoded. Results The cancer pain were completely relieved in 15 cases （25%）, partly relieved in 33 cases（55%）, slightly relieved in 12 cases （20%）. Conclusion Fentanyl intravenous continuous infusion with blastomory system is a safe, effective analgesic method for the cancer patient with severe pain.