精神分裂症患者复发与生活事件、自知力水平、服药依从性及社会支持的关系

Relationship of the recurrence of schizophrenia with life events, the level of insight, therapy compliance and social support

目的了解精神分裂症患者复发与生活事件、自知力水平、服药依从性及社会支持的关系，为能更好地预防复发提供依据。方法采用生活事件量表（LES）、自知力与治疗态度问卷（ITAQ）、服药依从性及社会支持评定量表（SSAS）对160例因复发而再次住院的精神分裂症患者（观察组）进行评定，并与86例首次住院且与观察组同期出院而未复发的精神分裂症患者（对照组）加以对照。结果①观察组生活事件发生率、负性生活事件数及负性生活事件值均显著高于对照组（P〈0．01）；②观察组ITAQ评分及SSAS总分、主观支持评分均显著低于对照组（P〈0．01）；③观察组服药完全依从者显著低于对照组，而服药部分依从及不依从者则显著高于对照组（P〈0．01）。结论频遭生活事件、自知力水平低、服药依从性差及社会支持缺乏的精神分裂症患者容易复发。

Objective To explore the relationship of the recurrence of schizophrenia with life events, the level of insight, therapy compliance and social support, so as to provide evidence for preventing relapse. Methods 160 schizophrenic inpatients （observation group） who were re -hospitalized because of recurrence, were evaluated with the life events scale （LES） , insight treatment attitude questionnaire （ITAQ）, drug therapy compliance and Social Support Assessment Scale （SSAS） . 86 non -relapse schizophrenic out -patients （control group）, who were discharged at the same time as observation group after the first hospitalization. Results ①The incidence rate of life events, the number of negative life events and the score of negative life events in observation group were higher than those in control group （ P 〈 0. 01 ） . ②The scores of ITAQ, SSAS and subjective support in observation group were lower than those in control group （P 〈0. 01 ） . ③The rate of complete drug therapy compliance in observation group was significantly lower than that in control group, while the rates of partially compliance and no - compliance of drug therapy in observation group were significantly higher than those in control group （ P 〈 0. 01 ） . Conclusions The schizophrenic patients with more life events, lower level of insight, bad therapeutic dependence and shortage of social support are liable to recur.