梅毒IgM抗体检测技术的现状

Advances in the detection of Treponema pallidum-specific IgM antibody

梅毒是由梅毒螺旋体引起的一种慢性传染病，主要通过性行为传播，也可通过母婴垂直传播，临床表现复杂。目前梅毒的诊断及疗效判断均依赖于实验室检测，其中血清学抗体检查起着重要作用。研究表明，IgM抗体检测有望成为梅毒早期感染、胎传梅毒、神经梅毒以及复发梅毒诊断的有效检测技术之一，对有关IgM抗体检测技术研究进展以及临床应用现状进行综述。

Syphilis, a chronic infectious disease caused by Treponema pallidum, often has complicated manifestations. Syphilis is spread mainly through sexual transmission, sometimes by maternal-to-infant vertical transmission. The diagnosis and efficacy evaluation of syphilis are commonly based on laboratory examination, especially on serological antibody detection. It has been demonstrated that specific IgM antibody detection is a prospective means for the diagnosis of early syphilis, congenital syphilis, neurosyphilis and recurrent syphilis. This article describes the tests most commonly used for the detection of Treponema pallidum-specific IgM antibody.