胃癌肝转移治疗方法的探讨

Discuss the treatments of hepatic metastases from gastric carcinoma

目的:探讨胃癌肝转移的外科治疗效果。方法:对本院1998年1月～2008年1月收治的原发性胃癌269例中伴肝转移的53例的临床资料进行回顾性分析。对其中施行同时性胃癌肝转移灶切除术(切除组)的18例和仅行胃癌切除术而未行肝转移灶切除术(未切除组)的35例的术后生存时间进行对比。结果:全组有50例获得随访。胃癌肝转移灶切除术后1年、3年和5年生存率分别为58.8%、17.6%和0;未切除组术后1年、3年和5年生存率分别为为57.6%、15.2%和0。两组术后生存时间差异无统计学意义(P>0.05)。结论:胃癌肝转移施行同时胃癌肝转移病灶切除术并不能有效改善病人的预后。

Objective： To investigate the effectiveness Of surgical treatment of hepatic metastatic tumor from gastric carcinoma. Methods： Clinical data of 53cases of hepatic metastatic tumor out of 269 patients with primary gastric cancer fi＇om Jan 1998 to Jan 2008 were analyzed retrospectively. A comparatives tudy was done on 18 cases（resection group） under going hepatectomy＋gastric cancer radi- cal operation vs 35 cases （nonresection group） only receiving gastric cancer Radical operation in the post operative survival time. Results： Among the whole team, 50 cases were followed up. Survival rates of 1 year, 3-year and 5-year were 58.8% ,17.6% and 0 after hepatic metastasis of gastric cancer lesions was removed; Survival rates of 1 year, 3-year and 5-year were 57.6%,15.2% and 0 after hepatic metastasis of gastric cancer lesions was not removed. Survival time of two groups had no significant difference （P〉0.05）. Conclusions： Although gastric cancer patients with hepatic metastasis were simultaneously administered with gastric cancer and hepatic metastasis lesions resection, the patients＇ prognosis cannot be effectively imoroved.