收缩后收缩识别高血压左心室舒张功能假性正常化的临床研究

The Clinic Study on Evaluation of Pseudonormalized Left Ventricular Diastolic Function in Patients with Hypertension by Postsystolic Shortening

目的探讨收缩后收缩(PSS)识别高血压患者左心室舒张功能假性正常化的临床意义。方法选择二尖瓣血流频谱舒张早期与心房收缩期流速之比(E/A)>1的高血压患者30例和正常对照组30例。使用定量组织速度成像(QTVI)技术,获取纵向上不同壁的基底段同步多普勒速度、时间速度积分曲线,测量其等容舒张时间、PSS振幅、PSS达峰时间及PSS持续时间,并求其平均值。结果高血压组等容舒张时间为(67.33±13.37)ms,正常组(56.67±12.13)ms,2组比较差异有统计学意义(P<0.05);高血压组在等容舒张期内出现病理性PSS,正常对照组则无。结论PSS评价高血压患者左心室舒张功能假性正常化,有一定的临床应用价值。

Objective To evaluate the role of postsystolic shortening（PSS） in assessing the pseudonormalized left ventricular diastolic function in patients with hypertension. Methods Thirty pseudonormalized left ventricular diastolic function in patients with hypertension and 30 normal persons （control group） were assessed by QTVI. After dynamic images were collected and information was ayalyzed, left ventricular myocardial velocity and time velocity integral profiles were acquired along long axis asynchronously in basal segments of different walls,isovolumic relaxation time,PSS amplitu＇de, time to PSS peak,and PSS duration were measured for their respective average. Results Isovolumic relaxation time[（67.33±13.37）ms] in hypertension group was lengthened obviously than control group[（56.67±12.13）ms]（P〈0.05）. There was postsystolic shortening in hypertension patient group,but was not in control group. Conclusion PSS plays an important role in assessing the pseudonormalized left ventricular diastolic function in patients with hypertension.