微创置管胸腔引流与常规胸腔穿刺治疗恶性胸腔积液的效果观察

Fine Catheter Thoracostomy Closed Drainage Versus Conventional Pleural Aspiration in the Treatment of Malignant Pleural Effusion

目的观察微创置管胸腔闭式引流与常规胸腔穿刺后注药治疗恶性胸腔积液的临床疗效。方法将58例恶性胸腔积液患者随机分成A(n=30)、B(n=28)2组,分别进行微创置管闭式引流和常规胸腔穿刺,并均于胸腔内注入化疗药物。结果A组胸腔积液控制的总有效率为83.3%,明显优于B组的57.1%(P<0.05)。结论应用微创置管引流恶性胸腔积液操作安全、简便,能最大限度地排净胸腔积液,对控制癌性胸腔积液有较好的疗效,能显著改善患者生活质量。

Objective To explore the clinical efficacy of fine catheter thoracostomy closed drainage and conventional pleural aspiration in the treatment of malignant pleural effusion. Methods 58 patients with malignant pleural effusions were randomly assigned to fine catheter thoracostomy closed drainage group （A group, n = 30） or conventional pleural aspiration group （B group,n=28）. Chemotherapeutic drugs were infused into the thoracic cavity in eligible patients after drainage. The therapeutic response was evaluated 4 weeks later. Results Overall response rate was 83.3% in A group and 57.1% in B group respectively （P〈0.05）. Conclusion Fine catheter thoracostomy closed drainage is a simple,safe and valid option for the treatment of malignant pleural effusion,which can improve the quality of life of patients with malignant pleural effusion.