期刊文献+

老年单纯收缩期高血压的循证治疗 被引量:1

Evidence-Based Treatment for An Elderly Patient with Isolated Systolic Hypertension
下载PDF
导出
摘要 目的借助循证医学的方法为老年单纯收缩期高血压患者确定治疗目标及治疗方案。方法在充分评估患者病情的基础上,根据PICO原则,提出临床问题并转换成便于检索的形式,检索Cochrane图书馆(2008年第1期)、MEDLINE(PubMed 1990年1月至2008年1月)和SUMsearch(1990年1月至2008年1月)等数据库,查找与老年单纯收缩期高血压治疗相关的系统评价和随机对照试验,并对相关证据进行评价。结果共检索出与不同问题相关的随机对照试验59篇,系统评价或Meta分析17篇。通过对检索结果进行分析,为患者制定了合理的治疗方案。经1年随访证实,该方案适合患者。结论采取循证治疗的方法,为确诊的老年单纯收缩期高血压患者制定合理的治疗目标和治疗方案,可有效提高治疗效果。 Objective To formulate an evidence-based treatment plan for an elderly patient with isolated systolic hypertension. Methods Based on an adequate assessment of the patient's condition and using the principle of PICO, we searched for systematic reviews and randomized controlled trials in The Cochrane Library(Issue 1, 2008), MEDLINE (PubMed, January 1990 to January 2008) and SUMsearch (January 1990 to January 2008), and evaluated the evidence. Results A total of 59 RCTs, and 17 systematic reviews were identified.A rational treatment plan was made upon a serious evaluation of the data. After one year follow-up, the plan was proved optimal. Conclusion Evidence- based approaches help us to prepare the most appropriate therapy plan for this patient and will help to improve the therapeutic effects for patients with isolated systolic hypertension.
作者 杨简 江洪
出处 《循证医学》 CSCD 2009年第2期105-109,共5页 The Journal of Evidence-Based Medicine
关键词 单纯收缩期高血压 随机对照试验 系统评价 循证治疗 isolated systolic hypertension randomized controlled trials systematic review evidence-based treatment
  • 相关文献

参考文献20

  • 1Guidelines Subcommittee. 1999 World Health Organization- international society of hypertension guidelines for the management of hypertension [J]. J Hypertens, 1999, (2): 151-183.
  • 2National High Blood Pressure Education Program Coordinating Committee. The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: The JNC 7 report [J]. JAMA, 2003,289(19): 2560-2572.
  • 3Sagie A, Larson MG, Levy D. The natural history of borderline isolated systolic hypertension [J]. N Engl J Med, 1993,329(26) : 1912-1917.
  • 4O'Donnell CJ, Ridker PM, Glynn RJ, et al. Hypertension and borderline isolated systolic hypertension increase risks of cardiovascular disease and mortality in male physicians [J]. Circulation, 1997,95 (5) : 1132-1137.
  • 5SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP) [J]. JAMA, 1991,265(24): 3255-3264.
  • 6Staessen JA, Fagard R, Thijs L, et al. Randomised doubleblind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators [J]. Lancet, 1997,350(9080) : 757-764.
  • 7Liu L, Wang JG, Gong L, treatment and placebo in older systolic hypertension. Systolic China) Collaborative Group [J] et al. Comparison of active Chinese patients with isolated Hypertension in China (Syst- J Hypertens, 1998,16(12 Pt 1):1823-1829.
  • 8Staessen JA, Gasowski J, Wang JG, et al. Risks of untreated and treated isolated systolic hypertension in the elderly: Metaanalysis of outcome trials [ J ]. Lancet, 2000,355 (9207) : 865- 872.
  • 9Hansson L, Zanchetti A. The Hypertension Optimal Treatment (HOT) study patient characteristics : Randomization, risk profiles, and early blood pressure results [J]. Blood Press, 1994,3 (5) : 322-327.
  • 10Somes GW, Pahor M, Short RI, et al. The role of diastolic blood pressure when treating isolated systolic hypertension [J]. Arch Intern Med, 1999,159(17):2004-2009.

同被引文献16

引证文献1

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部