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肺血管内皮细胞在慢性阻塞性肺疾病发病机制中的作用

Effects of pulmonary vascular endothelium cell in pathogenesis of chronic obstructive pulmonary disease
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摘要 慢性阻塞性肺疾病的发病机制是目前研究热点，肺血管内皮细胞在各种学说中均占有重要地位，本文概述了肺血管内皮细胞在慢性阻塞性肺疾病发病机制中的作用，以期指导临床找到早期诊断慢性阻塞性肺疾病的敏感指标。 The pathogenesis of chronic obstructive pulmonary disease is a hot research at present, pulmonary vascular endothelium cell plays an important part in each theory. The effects of pulmonary vascular endothelium cell in the pathogenesis of chronic obstructive pulmonary disease are overviewed,in order to help finding sensitive markers to diagnosis early chronic obstructive pulmonary disease.
作者 贝承丽 陈平
机构地区 中南大学湘雅二医院呼吸内科
出处 《国际呼吸杂志》 2009年第9期554-556,共3页 International Journal of Respiration
关键词 慢性阻塞性肺疾病 肺血管内皮细胞 发病机制 综述 Chronic obstructive pulmonary disease Pulmonary vascular endothelium cell Pathogenesis Overview
分类号 R563.9 [医药卫生—呼吸系统]
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参考文献16

  • 1吴杰.香烟暴露对大鼠肺组织及人血管内皮细胞MMP-9、TIMP-1表达影响[J].中国优秀硕士学位论文全文数据库,2007,(06).
  • 2马万里,李元桂,辛建保.基质金属蛋白酶及金属蛋白酶组织抑制剂在肺纤维化中的变化[J].华中科技大学学报（医学版）,2002,31(5):527-529. 被引量：15
  • 3谢丽华,陈平,陈芳,向旭东,周锐,吴尚洁.香烟提取物对人内皮细胞基质金属蛋白酶9和组织金属蛋白酶抑制剂1分泌的影响[J].中华结核和呼吸杂志,2006,29(10):715-716. 被引量：3
  • 4Segura-Valdez L,Pardo A, Gaxiola M, et al. Upregulation of gelatinases A and B, collagenases 1 and 2, and irtereased parenchymal cell death in COPD. Chest, 2000,117 : 684-694.
  • 5Dvorak HF. Vascular permeability factor/ vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol,2002,20:4368-4380.
  • 6Gille H,Kowalski J, Li B, et al. Analysis of biological effects and signalingproperties of Fit-1 (VEGFR-1) and KDR (VEGFR-2). A reassessmentusing novel receptor-specific vascular endothelial growth factor mutants. J Biol chen, 2001, 276:3222-3230,
  • 7Tuder RM, Petrache I, Elias JA, et al.Apoptosis and emphysema: the missing link. Am J Respir Cell Mol Biol, 2003,28:551-554.
  • 8Kasahara Y,Tuder RM,Cool CD, et al. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Meal,2001,163 (3 Pt 1):737-744.
  • 9Kanazawa H, Hirata K, Yoshikawa J. Imbalance between vascular endothelial growth factor and endostatin in emphysema. Eur Respir J, 2003,22 : 609-612.
  • 10Kanazawa H, Asai K, Hirata K, et al. Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease. Am J Meal,2003,114 354-358.

二级参考文献60

  • 1王爱民.基质金属蛋白酶[J].国外医学（临床生物化学与检验学分册）,1995,16(6):245-248. 被引量：21
  • 2姚根宏,郑春霞,陈惠萍,曾彩虹,刘志红,黎磊石.循环中内皮细胞损伤生物标志物在判断狼疮性肾炎肾脏血管病变中的应用[J].肾脏病与透析肾移植杂志,2006,15(4):311-315. 被引量：7
  • 3姚根宏,刘志红,陈惠萍,郑春霞,曾彩虹,黎磊石.循环内皮细胞在狼疮性肾炎血管病变诊断中的应用[J].肾脏病与透析肾移植杂志,2007,16(1):19-24. 被引量：14
  • 4Zimmerman BJ,Holt JW,Paulson JC,et al.Molecular determinants of lipid mediator-induced leukocyte adherence and emigration in rat mesenteric venules[J].Am J physiol,1994;266(3 pt 2):H847
  • 5Tosi MF,Stark JM,Smith CW,et al.Induction of ICAM-1 expression on human airway epithelial cells by inflammatory cytokines: Effects on neutrophil epithelial cell adhesion[J].Am J Respir cell Mol Biol,1992;7(2):214
  • 6Vignola AM,Campbell AM,Chanez P,et al.HLA-DR and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis[J].Am Rev Respir Dis,1993;148(3):689
  • 7Stefano AD,Maestrelli P,Roggeri A,et al.Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis[J].Am J Respir Crit Care Med,1994;149(3):803
  • 8Hayashi T, Stetler-Stevenson W G, Fleming M V et al.Immunohistochemical study of metalloproteinases andtheir tissue inhibitors in the lungs of patients with diffusealveolar damage and idiopathic pulmonary fibrosis. Am JPathol, 1996, 149:1241
  • 9Swiderski R E, Dencoff J E, Floerchinger C S et al. Dif-ferential experession of extracellular matrix remodelinggenes in a murine model of bleomycin-induced pulmonaryfibrosis. Am J Patol, 1998, 152:821
  • 10Montano M, Ramos C, Gonzalez G et al. Lung collage-nase inhibitors and spontaneous and latent collagenase ac-tivity in idiopathic pulmonary fibrosis and hypersensi-tivity pneumonitis. Chest, 1989, 96:1115

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国际呼吸杂志
2009年 第9期

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