摘要
为探讨充血性心力衰竭（CHF）患者的血浆一氧化氮（NO）含量及其意义，本文采用比色分析法测定了42例CHF患者的血浆NO浓度，结果发现，CHF患者的血浆NO（64．47±21．42μmol／L）显著高于对照组（51．62±13．62μmol／L），P＜0．005，其中心功能Ⅲ～Ⅳ级（按NYHA心功能分级标准）患者的血浆NO（78.8±10．85μmol／L）显著高于心功能Ⅱ组者（53.77±11．79μmol／L），P＜0.001。提示CHF患者的血浆NO水平增高，NO在CHF的发生发展中起重要作用，且与病情严重程度相关。
In order to study the level of plasma nitric oxide (NO) and its significance in patients with congestive heart failure (CHF), the plasma NO was measured in 42 patients with CHF by colorimetric analysis. The results showed that the level of plasma NO was significantly higher in patients with CHF (64. 47± 21.42μmol/L)than that in controls (51. 62± 13. 62μmol/L), P<0. 005, and in which the level of plasm NO was significantly higher in NYHA functional class Ⅲ ~ Ⅳ (78. 28± 10. 85μmol/L) than that in class Ⅱ (53. 77± 11. 79μmol/l), P<0. 001. The results indicated that there was a increased level of plasma NO in CHF. The plasma NO plays an important role in the development of CHF and the level of NO was associated with the degree of CHF.
出处
《急诊医学》
CSCD
1998年第1期37-38,共2页
