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甲胎蛋白的促增殖作用与不良妊娠结局关系的探讨 被引量:1

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摘要 本文对2501例孕妇孕中期的MSAFP水平及不良妊娠结局进行了观察。见孕中期MSAFP异常升高组的不良妊娠结局发生率明显高于正常组。还以体外实验证实了AFP对胚胎细胞的促增殖作用。提示AFP在体内的促细胞增殖作用受到影响,很可能就是造成流产、早产、IUGR、死胎死产等不良妊娠结局的直接原因。
出处 《中国优生优育(1990-2002上半年)》 1998年第1期1-3,共3页 Journal of Improving Birth Outcome and Child Development of China
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参考文献4

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同被引文献10

  • 1Jaffa A, Yaron Y, Har Joov J, Amester R, Legum C, Lessing JB. Doppler velocimetry of the umbilical artery as a predictor so outcome in pregnancies characterized by elevated maternal serum and normal amniotic fluid alpha-fetoprotein. Fetal Dissgn Ther,1997, 12: 85-88.
  • 2Brazerol WF, Grover S, Donnenfeld AE. Unexplained elevated maternal serum α-fetoprotein levels and perinatal outcome in an urban clinic population. Am J Obstet Gynecol, 1994, 171: 1030.
  • 3Triple marker screening for trisomy 21, trisomy 18 and open neural tube defects in singleton pregnancies of native Japanese pregnant women. J Obstet Gynaecol Res, 2000, 12 (1): 26.
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  • 6Wald N J, Densem JW, Smith D et al. Four marker serum screening for Down' s syndrome. Prenat Diagn, 1994, 14:707.
  • 7Brock D J, Barron L, Jelen Pwatt M, Scrimgeour JB. Maternal serumalpha-fetoprotein measurements as an early indicator of low birthweight. Lancet, 1977, 2:267-268.
  • 8Katz VL, Chescheir NC, Cefalo RC. Unexplained elevations of maternal serum alpha-fetoprotein. Obstet Gynecol Surv, 1990, 45:719-726.
  • 9鲍培忠.多种血清标记物在产前筛查中作用的综合评价[J].国外医学(计划生育分册),1999,18(2):74-78. 被引量:56
  • 10庞泓,冯光,宋奉霞,康云玲,张丽.孕妇血清标志物用于出生缺陷的产前筛查[J].中国优生与遗传杂志,2002,10(6):99-100. 被引量:12

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