成人急性呼吸道感染患者衣原体的检测

Acute respiratory tract Chlamydia infection in adult patients

目的：探讨衣原体在成人呼吸道感染的分布。方法：应用单克隆抗体免疫荧光法检测８２例呼吸道感染患者鼻咽部分泌物中的衣原体，同时检测支原体和四种病毒。对衣原体阳性患者应用间接免疫荧光法检测双份血清特异性ＩｇＧ（ＳＩｇＧ）抗体。结果：（１）衣原体阳性１６例，检出率２０％。（２）不同病种、不同年龄组检出率比较差异无显著性意义。（３）衣原体阳性患者同时合并其它病原体混合感染率高。（４）衣原体阳性和阴性组双份血清ＳＩｇＧ≥４倍增高率比较差异有显著性意义。结论：衣原体是成人呼吸道感染的一个重要病原，可引起不同年龄成人的各种急性呼吸道感染，混合感染为其特点。

Objective:To study the distribution of Chlamydia in respiratory infection in adults.Methods:the nasopharynx secretions from 82 adult patients with respiratory tract infection were detected for Chlamydia by monoclonal antibody (McAb) with immunoflurescent assay. At the same time, mycoplasma and other four kinds of virus were also detected. And the special IgG(SIgG) were determined in the double sera of Chlamydia positive patients by indirect immunoflurescent method. Results:(1) 16 patients were Chlamydia postive (20.0%). (2)The difference of Chlamydia positive rate in different disease groups and age groups showed no significance. (3)The rate of mixed infection was high in the Chlamydia positive patients.(4)The rate of SIgG≥4 fold in the double sera was markedly different (P<0.05). Compared the Chlamydia positive group with the controls.Conclusion:Chlamydia is one of the important pathogens of respiratory tract infection in adults. It may cause different forms of acute respiratory tract infection in different age of adults. The mixed infection is characteristic.