子宫动脉分级层进式栓塞治疗子宫肌瘤临床研究

Clinical Study of uterine artery embolization with sequential procedure for treating hysteromyoma

目的评价适量平阳霉素超液化碘油乳剂、明胶海绵微末、明胶海绵条分级序贯(层进式)栓塞子宫动脉治疗子宫肌瘤的安全性和疗效。方法回顾性分析两组栓塞剂介入治疗子宫肌瘤并发症、疗效情况,A组即研究组、B组为对照组:PVA颗粒(300～500Hm)。结果A组较B组术后疼痛程度略重、住院日稍长,而误栓的可能低于B组,子宫缺血坏死、继发感染均为零。A组缩短月经期、减少月经量、缩小肌瘤体积及缓解相关肌瘤压迫症状均优于B组,治疗后12个月、24个月复发可能性更低。结论分级序贯栓塞法治疗子宫肌瘤安全、经济、高效。

Object To evaluate the clinical therapeutic effect and safety of uterine artery embolization with sequential procedure on hysteromyoma. Method： Retrospectively analysis was made in two groups of patients with hysteromyoma received UAE. The experimental group （Group A） used pingyangmycin super-liquation iodipin cream gelatin sponge micro-powder, gelatin sponge stripe and the control group （Group B） used PVA granules（300 500Hm）. Result： Compared with patients of Group B, the patients of Group A were a little more painful and had longer hospitalization but with lower rate of ectopia embolism. There was no ischemic and necrosis of uterus and secondary infection in group A. Group A was better than B in shortening menstrual period, decreasing menstrual blood volume and hysteromyoma volume, relieving tumor oppression symptom. There were fewer recrudescence in 12 and 24 months in group A than in group B. Conclusion： Uterine artery embolization with sequential procedure on hysteromyoma is safe, cheap and effective.