纤溶酶治疗下肢深静脉血栓的临床研究

目的观察纤溶酶治疗下肢深静脉血栓的临床疗效。方法将87例下肢深静脉血栓患者随机分为治疗组(44例)和对照组(42例)进行对比研究,治疗组采用纤溶酶静脉输入,对照组采用低分子右旋糖酐加丹参静滴治疗。结果纤溶酶治疗下肢深静血栓疗效优于对照组,经统计学处理,差异具有统计学意义("P<0.05")。结论纤溶酶治疗下肢深静脉血栓在临床症状、体征明显改善或消失的同时,血液流变学的指标也明显好转,无明显并发症,具有较好的临床疗效,值得进一步观察研究和应用。

Objective To investigate the treatment effect of deep venous thrombosis of lower extremities with fibrinolysin. Methods 87 patients with deep venous thrombosis of lower extremities were divided into treatment group（44cases）and control group（42cases）randomly.The treatment group was treated with fibrinolysis intervenous drop infusion, and the control group was treated with dextran-40 and salvia miltiorrhiza intravenous drop infusion. Estimate the treatmenteffect of fibrinolysin by comparing the clinical results of these two groups. Result The treatment result of fibrinolysin injection was much better than the control group significant differences （P〈0.05）. Conclusion The treatment with fibrinolysin can significantly relieve the symptoms and signs of deep venous thrombosis of lower extremities, and can also improve the index ofhemorheology, without appart complications. So it is a safe and effective drug for further research and clinical appkication .