鼻塞式持续气道正压通气在新生儿呼吸衰竭中的应用

目的比较鼻塞式持续气道正压(NCPAP)通气和头罩或鼻导管给氧对新生儿呼吸衰竭的疗效。方法将36例胎龄为32～37周、呼吸衰竭的新生儿随机分为治疗组20例,对照组16例。在综合治疗的基础上,治疗组给予NCPAP治疗,对照组给予鼻导管吸氧,对两组患儿的疗效进行比较。结果治疗组治疗后0.5～6h,血Pa02及SaO2升高,血PaC02下降;对照组病例给氧6h后Pa02、PaC02改善仍不明显。治疗组显效率(85.0%)高于对照组(56.3%),有显著性差异(P<0.01)。应用NCPAP期间无明显并发症。结论NCPAP对新生儿呼吸衰竭有良好疗效,无明显不良反应,值得临床推广应用。

Objective To compared the effect of the nasal continuous positive airway pressur （NCPAP） and nasal catheter supplyed oxygen in treatment of neonatal respiratory failure. Methods Fetal 32 - 37 weeks age of the neonatal respiratory failure were？divided into the treatment group（n=20） and the control group（n=16） at randomly. On the basis of combined therapy, the treatment group were treated with NCPAP, while the control group were gave nasal catheter. The effect in the two groups at the end of the treatment were compared .Results The PaO2 as well as SaO2 increased and PaCO2, FiO2 decreased, the improvement of PaO2, PaCO2 after supplying oxygen 6 hours was not obvious.The obvious effective rate in the treatment group was higher than the control group with 85.0% to 56.3%. there was significant difference （P〈0.01）. There was no obvious complications between using NCPAR Conclusion NCPAP has good effect in treating neonatal respiratory failure, it has no obvious adverse reaction, it is worth extending application in clinic.