瞬目反射在糖尿病患者中的应用

The application of blink reflex in diabetes mellitus

目的观察糖尿病患者瞬目反射（BR）的特点并探讨其临床意义。方法检测40例糖尿病患者及30例健康成人BR。结果糖尿病组R1、R2和R2’波的潜伏期（ms）分别为（10．89±2．38）、（34．73±3．63）、（36．04±4．43）较对照组明显延长，且以R2和R2’延长显著，其波幅（uv）分别为（249±58）、（185±50）、（159±45），较对照组明显降低，表明糖尿病性中枢神经系统损害可影响脑干。随糖尿病病程的延长BR的异常率逐渐升高。结论BR可作为糖尿病性中枢神经系统损害客观而灵敏的指标。

Objective To study the characteristics and clinical value of blink reflex in patients with diabetes mellitus. Methods Blink reflex were measured in 40 diabetes melletus and 30 normal adults. Results The result showed that diabetic group R1, R2 and R2＇ wave latency was significantly longer than the control group, meanwhile their amplitudes were significantly lower than that of control. And to R2 and R2＇ extended significantly,which showed that the damage to the central nervous system in diabetes can affect the brain stem. With the extension of duration of diabetes BR abnormal rate gradually increased. Conclusion It was concluded that BR provide an objective and sensitive index for the damage of the central nervous system in diabetes.