苎麻根化学成分研究

Chemical constituents in roots of Boehmeria nivea

目的研究荨麻科苎麻属植物苎麻Boehmeria nivea根中的化学成分。方法反复利用色谱方法进行分离纯化,通过波谱分析、化学方法及参照文献鉴定单体成分结构。结果从苎麻根石油醚部位分离得到7个化合物,分别鉴定为胡萝卜苷-10,13-二十碳二烯酸酯(Ⅰ)、胡萝卜苷(Ⅱ)、β-谷甾醇(Ⅲ)、三油酸甘油酯(Ⅳ)、白桦酸(Ⅴ)、齐墩果酸(Ⅵ)、19α-羟基乌苏酸(Ⅶ)。结论化合物Ⅰ为新化合物,命名为苎麻根甲素(niveain A),化合物Ⅳ为首次从该属植物中分离得到。

Objective To investigate the chemical constituents in the roots of Boehmeria nivea. Methods The constituents were isolated by repeated column chromatography and their structures were elucidated by chemical properties and spectroscopic analyses. Results Seven compounds were isolated and their structures were identified to be daucosterol-10, 13-eicosdienoate （ Ⅰ ）, daucosterol （ Ⅱ ）, 13-sitosterol （ Ⅲ ）, olein （Ⅳ）, betulinic acid （Ⅴ）, oleanolic acid （Ⅵ）, 19α-hydroxyursolic acid （Ⅶ）. Conclusion Compound Ⅰ is a new compound named niveain A, compound IV is obtained from the plants of Boehmeria Jacq. for the first time.