不同状态糖尿病患者胃电活动的特点

Characteristics of gastric myoelectrical activity in diabetic patients

目的:观察不同状态糖尿病患者的胃电活动特征,探讨糖尿病胃电紊乱的发展规律.方法:2005-11/2006-05北京协和医院就诊的糖尿病患者54例,根据糖尿病并发症及上消化道症状的有无分为3组:无并发症及上消化道症状组,有并发症而无明显上消化道症状组,有并发症及明显上消化道症状组.记录空腹30min和餐后60min的体表胃电活动.结果:糖尿病患者胃电节律异常发生率为74.1%.餐前胃电活动表现为:正常节律(46.3%)、胃动过缓(31.5%)、无节律(14.8%)、胃动过速(7.4%);餐后胃电活动表现为:胃动过缓(37%)、正常节律(35.2%)、无节律(20.4%)、胃动过速(7.4%).有并发症及上消化道症状组的PR值显著高于无并发症及上消化道症状组(1.07±1.17vs0.93±0.14,P=0.022).有并发症及上消化道症状者早饱症状的严重程度和PR值负相关(r=-0.535,P=0.040).结论:糖尿病患者胃电节律紊乱以胃动过缓最常见,不同状态糖尿病患者的胃电活动存在差异.

AIM： To investigate the gastric myoelectrical activity in diabetic patients in different stages. METHODS： Fifty-four patients with DM were included in this study, 24 males and 30 females, with a mean age of 59.9 ± 11.6 years. The patients were divided into three groups： group Ⅰ without both complications and upper gastrointestinal symptoms, group Ⅱ with complications but without severe upper gastrointestinal symptoms, group Ⅲ with both complications and severe upper gastrointestinal symptoms. EGG were performed30 minutes preprandial and 60 minutes postprandial. RESULTS： A total of 74.1% diabetic patients had dysrythmia. In the fasting state, 46.3% had normogastria, 31.5% had bradygastria, and 14.8% had arrhythmia. In postprandial, 46.3% had normogastria, 31.5% had bradygastria, and 14.8% arrhythmia. The power ratio of postprandial and preprandial was elevated in group Ⅲ compared to group Ⅰ （1.07± 1.17 vs 0.93 ± 0.14, P = 0.022）. There was a negative correlation between PR and satiety in group Ⅲ （r = -0.535, P = 0.040）. CONCLUSION： Bradygastria is significantly more common during the entire period of recording. Different EGG presentations are seen in patients with DM in different conditions.