甲砜霉素用于细菌性阴道病的临床观察

Thiamphenicol in Bacterial Vaginosis Treatment:A Clinical Analysis

目的观察甲砜霉素治疗细菌性阴道病的有效性。方法将260例细菌性阴道病患者随机分为甲砜霉素组与甲硝唑组各130例,甲砜霉素组给予甲砜霉素0.5 g,3次/d口服;甲硝唑130例给予甲硝唑0.2 g,3次/d口服,两组连续用药7 d,停药3 d后复查,并观察其不良反应。结果甲砜霉素组治疗细菌性阴道病的总有效率为95.38%,甲硝唑组治疗细菌性阴道病的总有效率为93.07%,二者差异无统计学意义(P>0.05),甲砜霉素组的不良反应明显少于甲硝唑组差异有统计学意义(P<0.01)。结论甲砜霉素治疗细菌性阴道病安全有效,不良反应小。

OBJECTIVE To smdy the efficiency of thiamphenicol in the treatment of bacterial vaginosis. METHODS All the 260 patients were allocated into two groups randomly; 130 patients were treated by thiamphenicol and 130 cases by metronidazole for 7 days continuously. All patients were investigated in the three days after finishing the treatment, observing the side effects. RESULTS The efficient rate of treating baterial vaginosis with thiamphenicol was 95.38%, the other was 93.07% （P〉0.05）. The side effects of thiamphenieol was more little than the other. CONCLUSIONS The treatment bacterial vaginosis with thiamphenicol is effective and safe and the side effects is a little.