多通道腔内阻抗技术在胃食管反流病诊断中的应用

Application of Multichannel Intraluminal Impedance Technique in the Diagnosis of Gastroesophageal Reflux Disease

24h食管pH监测有助于诊断胃食管反流病（GERD），但其只能发现pH〈4的酸反流。多通道腔内阻抗（MII）技术通过记录食管腔内食团通过所引起的阻抗值变化，可在多种食管水平上发现胃食管反流事件而不依赖于反流物的pH值，同步联合pH监测可明确反流物的酸度、反流持续和清除时间、反流到达近端食管的高度等。本文就MII技术及其在GERD诊断中的临床应用作一综述。

24-hour esophageal pH monitoring is helpful for the diagnosis of gastroesophageal reflux disease （GERD）. However, it can only detect acid reflux at pH〈4. Multichannel intraluminal impedance （MII） technique can record the changes of impedance value in the esophageal lumen caused by the passage of a bolus, and can detect gastroesophageal reflux events at multiple levels of the esophagus independent of the pH of refluxate. The acidity, duration and clearance time, and level of refluxate attained in the proximal esophagus can be detected by MII combined synchronously with pH monitoring. This article reviewed the MII technique and its clinical application in the diagnosis of GERD.