奥曲肽联合奥美拉唑治疗肝炎后肝硬化并上消化道出血的疗效观察

Therapeutic Effect of Octreotide Plus Omeprazole on Upper Gastrointestinal Hemorrhage With Posthepatitic Cirrhosis

目的观察奥曲肽联合奥美拉唑治疗肝炎后肝硬化并上消化道出血的疗效。方法将确诊的76例肝炎后肝硬化并上消化道出血患者随机分为2组。治疗组采用奥曲肽静脉微泵注射联合奥美拉唑的治疗方案,对照组采用垂体后叶素联合奥美拉唑的方案,疗程为3天。结果治疗组在止血有效率、止血时间上均明显优于对照组(P<0.05)。结论奥曲肽联合奥美拉唑治疗肝炎后肝硬化并上消化道出血比对照组更高效、安全、副作用少。

Objective To observe the therapeutic effect of octreotide plus omeprazole on upper gastrointestinal hemorrhage with posthepatitic cirrhosis. Methods 76 definite patients were randomly divided into two groups. The treatment group were injected octreotide plus omeprazol for 3 days, the control were group injected hypophysin plus omeprazol for 3 days. Results The haemostasis effecttive rate and haemostasis time of the treatment group are significantly superior to the control group （ P 〈 0.05 ）. Conclusion Octreotide plus omeprazole has a better clinical therapeutic effect and less side effect on treating upper gastrointestinal hemorrhage with posthepatitic cirrhosis.